Which type of cancer is Trastuzumab used to treat?

Trastuzumab is a monoclonal antibody primarily used in the treatment of cancers that overexpress the HER2 (human epidermal growth factor receptor 2) protein. One of the main indications for Trastuzumab is gastric carcinoma, particularly in cases where cancer cells are HER2-positive. By binding to the HER2 protein, Trastuzumab inhibits cell proliferation and triggers immune system responses against the cancer cells.

In contrast, the other types of cancer listed do not specifically involve HER2 overexpression as a defining feature. Hodgkin lymphoma is primarily treated with chemotherapy and radiation, and while Multiple myeloma and Ovarian cancer have their own specific targeted therapies and treatment protocols, they do not typically utilize Trastuzumab as part of their treatment regimen. Therefore, gastrically-associated tumors that are HER2-positive represent the correct and most effective target for Trastuzumab therapy.